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Nick Lane

nick.lane@ucl.ac.uk

 

PUBLICATIONS

Books

  1. Lane, Nick. CHASM: The Outlandish Origins of Complex Life. (to be published by WW Norton/Profile in 2014)

  2. Lane, Nick. Life Ascending: The Ten Great Inventions of Evolution. WW Norton/Profile, 2009

  3. Lane, Nick. Power, Sex, Suicide: Mitochondria and the Meaning of Life. OUP, Oxford, 2005

  4. Fuller BJ, Lane N, Benson EE, (Eds.) Life in the Frozen State. CRC Press, Boca Raton, 2004

  5. Lane, Nick. Oxygen: The Molecule that made the World. OUP, Oxford, 2002

 

Articles

  1. Lane N. Thermodynamics, formamide, and the origin of life. Physics of Life Reviews doi:10.1016/j.plrev.2012.01.005; 2012.

  2. Hadjivasiliou Z, Pomiankowski A, Seymour R, Lane N. Selection for mitonuclear co-adaptation could favour the evolution of two sexes. Proc Roy Soc Bdoi:10.1098/rspb.2011.187; 2011

  3. Lane N. The costs of breathing. Science, 334: 184-185; 2011.

  4. Lane N. Mitonuclear match: optimizing fitness and fertility over generations drives aging within generations. BioEssays, 33: 860-869; 2011.

  5. McInerney JO, Martin W, Koonin EV, Allen JF, Galperin MY, Lane N, Archibald JM, Embley TM. Planctomycetes and eukaryotes: a case of analogy not homology. BioEssays 33: 810-7; 2011.

  6. Kitazoe Y, Kishino H, Hasegawa M, Matsui A, Lane N, Tanaka M. Stability of mitochondrial membrane proteins in terrestrial vertebrates predicts aerobic capacity and longevity. Genome Biol. Evol 3: 1233-1244; 2011.

  7. Lane N. Energetics and genetics across the prokaryote-eukaryote divide. Biology Direct 6: 35; 2011.

  8. Lane N. Plastids, genomes and the probability of gene transfer. Genome Biol. Evol. 3: 372-374; 2011.

  9. Lane N, Martin W. The energetics of genome complexity. Nature, 467: 929-934; 2010.

  10. Lane N. Why are cells powered by proton gradients? Nature Education, 3(9):18; 2010.

  11. Lane N. Chance or necessity? Bioenergetics and the probability of life. J Cosmology 10: 7; 2010.

  12. Lane N. Genesis revisited. New Scientist, 7 August: 36-39; 2010.

  13. Lane N. Intelligent non-design and the origins of life. J Cosmology 8: 16; 2010.

  14. Lane N, Allen JF, Martin W. How did LUCA make a living? Chemiosmosis in the origin of life. Bioessays 32: 271-280; 2010.

  15. Lane N. Life's a gas. New Scientist, 6 February: 36-39; 2010.

  16. Lane N. On the origin of barcodes. Nature 462: 272-274; 2009.

  17. Lane N. Cradle of life. New Scientist, October 17: 38-42; 2009.

  18. Lane N. Why sex is worth losing your head for. New Scientist 13 June: 40-43; 2009.

  19. Lane N. The furnace within. New Scientist 07 February: 42-45; 2009.

  20. Lane N. New light on medicine. Revised and updated for Scientific American special issue on cancer, July 2008.

  21. Lane N. One baby, two mums. New Scientist, 7 June: 38-41; 2008.

  22. Lane N. Origins of Death. Nature 453: 583-585; 2008.

  23. Lane N. Low variability on the W chromosome in birds is more likely to reflect selection on mitochondrial genes. Heredity, February 2008.

  24. Lane N. What's in the rising tide? Nature 449: 778-780; 2007.

  25. Lane N. Reading the book of death. Nature 448: 122-125; 2007.

  26. Lane N. Power games. Nature, 443: 901-903; 2006.

  27. Lane N. What can’t bacteria do? Nature, 441: 274-7; 2006.

  28. Lane N. Powerhouse of disease. Nature, 440: 600-2; 2006.

  29. Lane N. Plugging the mitochondrial leak. The Scientist, 20: 34; 2006.

  30. Lane NJ. A unifying view of aging and disease: the double agent theory. J Theoret Biol 225 (4): 531-540; 2003.

  31. Lane NJ. New light on medicine. Scientific American, January 2003

  32. Lane NJ. Born to the purple: the story of porphyria. Scientific American online, December 2002

  33. Lane NJ. The Big O. New Scientist, December 14, 2002

  34. Lane NJ. Medical constraints on the quantum mind. Review article. J Roy Soc Med 93: 571-575; 2000

  35. Lane NJ. Blood ties. The Sciences. New York Academy of Sciences. Sept/Oct pp 24-29, 1998; discussion Jan/Feb 1999

  36. Lane NJ, Allen K. Hyponatraemia after orthopaedic surgery: Ignorance of the effects of hyponatraemia after surgery is widespread - and damaging. Editorial. BMJ 318: 1363-1364; 1999; discussion in BMJ 319: 514-516; 1999

  37. Lane NJ. Common sense, nonsense and statistics. Personal paper. J Roy Soc Med; 92: 202-205; 1999; reprinted with commentary in Contemp Rev Obstet Gynaecol Sept 1999; 149-153

  38. Lane, NJ. Thrombolytic therapy for acute ischaemic stroke. Letter. Lancet 350: 1475-1476; 1997

  39. Lane NJ. Radical Problems in Renal Transplantation. Biologist 1996; 43: 110-113

  40. Lane NJ, Thorniley MS, Manek S, Fuller BJ, Green CJ. The effect of mannitol and polyethylene glycol on the action of frusemide during renal storage and transplantation. Transplantation 62: 575-582; 1996

  41. Lane NJ, Thorniley MS, Manek S, Fuller BJ, Green CJ. Hemoglobin oxygenation kinetics and secondary ischemia in renal transplantation. Transplantation 61: 689-696; 1996

  42. Lane NJ, Thorniley MS, Manek S, Fuller BJ, Green CJ. Iron chelation, respiratory chain function and tubular necrosis in renal transplantation. Biochem Soc Trans 23: 524S; 1995.

  43. Lane NJ, Thorniley MS, Manek S, Fuller BJ, Green CJ. Iron chelation and respiratory chain function in vivo in renal ischaemia-reperfusion injury. Abstract. Clin Sci 89: 31P; 1995

  44. Lane NJ, Thorniley MS, Manek S, Fuller BJ, Green CJ. Inhibition of leukotriene B4 synthesis does not prevent development of acute renal failure following storage and transplantation. Transplantation 58: 1303-1308; 1994

  45. Lane NJ, Thorniley MS, Manek S, Green CJ. Vascular congestion does not correlate with mitochondrial dysfunction following renal transplantation. J Pathol 172 (suppl): 138A; 1994

  46. Thorniley MS, Lane NJ, Manek S, Green CJ. Non-invasive measurement of respiratory chain dysfunction following hypothermic renal storage and transplantation. Kidney Int 45: 1489-1496; 1994

  47. Thorniley MS, Lane NJ, Manek S, Green CJ. Non-invasive monitoring of renal haemoglobin oxygenation kinetics following hypothermic storage and transplantation. Biochem Soc Trans 21: 501S; 1993

  48. Thorniley MS, Lane NJ, Green CJ. Non-invasive monitoring of renal tissue oxygen sufficiency for transplantation. Clin Sci 85: 22P; 1993

  49. Thorniley MS, Lane NJ, Manek S, Green CJ. In vivo monitoring of respiratory chain dysfunction following renal storage and transplantation. Biochem Soc Trans 21: 500S; 1993

  50. Gower JD, Lane NJ, Goddard JG, Manek S, Ambrose IJ, Green CJ. Ebselen: Antioxidant capacity in renal preservation. Biochem Pharmacol 43: 2341-2348; 1992

  51. Toffa SEK, Fuller BJ, Gower JD, Lane NJ, Green CJ. Oxygen-free reperfusion of ischaemic kidneys. Int J Rad Biol 62: 116; 1992

 

Book chapters

  1. Lane N. The evolution of oxidative stress. In: Principles of Free Radical Biomedicine. Eds. Pantopoulos K, Schipper H. Nova Science Publications Inc, Hauppauge, NY, 2011.

  2. Lane, N. Mitochondria: Key to complexity. In: Martin, W (ed), Origins of Mitochondria and Hydrogenosomes. Springer, Heidelberg, Germany 2006.

  3. Lane N. The future of cryobiology. In: Life in the Frozen State, Eds: Fuller B, Lane NJ, Benson EE. Taylor and Francis, London, 2004.

  4. Thorniley MS, Lane NJ, Simpkin S, Fuller BJ, Jenabzadeh MZ, Green CJ. Monitoring of mitochondrial NADH levels by surface fluorometry as an indication of ischaemia during hepatic and renal transplantation. In Oxygen Transport to Tissue Vol XVII (Eds Ince C, Kesecioglu J, Trelci I, Apkir K); Plenum Press, New York, 1996, pp 431-444.

 

Features for EuroTimes (European Society for Cataract and Refractive Surgeons)

1. Lane N. Darwin and the evolution of the eye. EuroTimes (ESCRS) June 2009.

2. Lane N. MRSA: The rising menace. EuroTimes (ESCRS) October 2008.

3. Lane N. Who is paying the piper? Open access journals. EuroTimes (ESCRS) January 2008.

4. Lane N. Beyond the IOL. EuroTimes (ESCRS) September 2007.

5. Lane N. To block or not to block: Is blue light the enemy? EuroTimes (ESCRS) July 2007.

6. Lane N. Cannabis and glaucoma - the inside story. EuroTimes (ESCRS) April 2007.

7. Lane N. The great accomodation debate. EuroTimes (ESCRS) January 2007.

8. Lane N. Mitochondria – alpha and omega of retinal disease? EuroTimes (ESCRS) September 2006.

9. Lane N. Pioneers past and present; but where are the boundaries of the justifiable? EuroTimes (ESCRS) January 2006.

10. Lane N. New VEGF antagonists in AMD: new quandaries abound. EuroTimes (ESCRS) November 2005.

11. Lane N. Stem cells in ophthalmology: dawn of a new era? EuroTimes (ESCRS) October 2005.

12. Lane N. Ophthalmic gene testing: ready for prime time? EuroTimes (ESCRS) August 2005.

13. Lane N. Conflict of interest crisis: researchers and regulators at odds over reform proposals. EuroTimes (ESCRS) June 2005.

14. Lane N. Evidence-based medicine – never better than the evidence itself. EuroTimes (ESCRS) June 2004.

15. Lane N. Rheopheresis: ready for prime time? EuroTimes (ESCRS) November 2004.

16. Lane N. Vision 2020: Eliminating preventable blindness in the developing world? EuroTimes (ESCRS) February 2004.

17. Lane N. EMEA on the brink of the new EU. EuroTimes (ESCRS) November 2003.

18. Lane N. Antioxidants: who do you believe? EuroTimes (ESCRS) October 2003.

19. Lane N. Verteporfin’s efficacy in AMD comes into focus. EuroTimes (ESCRS) August 2003.